October 1, 2003—The Occupational Safety and Health Administration (OSHA) has revised its Safety and Health Topics Page concerning Isocyanates. The page explains which OSHA standards apply, gives some examples of hazards and possible solutions, and offers links to information on chemical sampling and analysis methods as well as to related topics, training, and additional resources.
Jobs that may involve exposure to isocyanates, which are the raw materials all polyurethane products are made of, include painting, foam-blowing, and the manufacture of many products, such as chemicals, polyurethane foam, insulation materials, surface coatings, car seats, furniture, foam mattresses, under-carpet padding, packaging materials, shoes, laminated fabrics, polyurethane rubber, adhesives, and other polyurethane products.
Health effects of isocyanate exposure include irritation of skin and mucous membranes, chest tightness, and difficult breathing. Isocyanates are classified as potential human carcinogens and are known to cause cancer in animals. The main effects of overexposure are occupational asthma and other lung problems, as well as irritation of the eyes, nose, throat, and skin.